Substrate: CD3 zeta (T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase))
Seq-ID: P20963 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-60782   LCK_HUMAN
MINT-7301967   NCK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
transmembrane receptor activity		 cytoplasm,
integral to membrane		 interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 58 ALFLRVKFSRSADAPAYQQGQ - 15144186
HTP
0.91
 - -
0.25
 - medium
Y 64 KFSRSADAPAYQQGQNQLYNE - 15144186
HTP
0.49
 - -
0.41
 - medium
Y 64 KFSRSADAPAYQQGQNQLYNE - 15592455
HTP
0.49
 - -
0.41
 - medium
Y 64 KFSRSADAPAYQQGQNQLYNE - 16094384
HTP
0.49
 - -
0.41
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15144186
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE Fyn 8578591
LTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 12522270
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15144186
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15592455
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 16094384
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15659558
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 18083107
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 123 ELQKDKMAEAYSEIGMKGERR Fyn 8578591
LTP
1.00
 LIG_TYR_ITAM
 Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.49
 - medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 12522270
HTP
1.00
 LIG_TYR_ITAM
 Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.49
 - medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 16094384
HTP
1.00
 LIG_TYR_ITAM
 Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.49
 - medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 15659558
HTP
1.00
 LIG_TYR_ITAM
 Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.49
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 153 QGLSTATKDTYDALHMQALPP - 16094384
HTP
0.90
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 153 QGLSTATKDTYDALHMQALPP - 15659558
HTP
0.90
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium

Substrate: CD3 zeta (T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase))
Seq-ID: P24161 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transmembrane receptor activity,
protein binding		 integral to membrane,
alpha-beta T cell receptor complex		 T cell receptor signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 153 QGLSTATKDTYDALHMQTLAP - 2139725
LTP
1.00
 - ITAM
0.60
 - low

Valid HTML 4.01 Transitional